The invention relates to a remarkably simple method for the in vitro production of three-dimensional, vital and mechanically stable cartilage or bone tissue and to the use thereof as a transplantation material for treating cartilage or bone defects and degenerative diseases such as rheumatism or arthrosis, and to the use thereof in testing active substances and physical factors. In the method a device is used, which is moved close to a fabric transporting the web threading tail and by means of which the web threading tail is detached from the surface of the fabric. The lock platearm may extend into the cutting head from the top, bottom, or side. Thus, the dimension of the detected signals can be decreased. Small PAM particles produced in such a mill are essentially all soluble in plain water within about 10 seconds.