A multi ratio drive including a first drive chain having a first drive chain engaged state and a first drive chain disengaged state; and a second drive chain having a second drive chain engaged state and a second drive chain disengaged state. The apparatus may further include a sheath such that at least one of the needle or tunneling device and sheath is echogenic. The first substrate provides a base substrate, and the second substrate provides a cap substrate. The method still further includes removing an amount of solution from the intermediate vial and placing the solution from the intermediate vial into the start vial. An alarm is generated if the number of target IP addresses associated with the connection requests from the source key exceeds a threshold.