A CMOS class AB output stage provides the advantages of high speed operation, low supply voltage requirements, and low quiescent current draw, resulting from the use of subthreshold biasing of the output driver transistors. Cross-dock and staging functions are combined at one facilitya super cross-dockso that suppliers to a large-scale manufacturer with multiple assembly plants may make deliveries of supplies to a single facility that services the multiple assembly plants. The outer sheet has non-thermocompressed regions surrounded by a plurality of thermocompression-bonded spots. The counter produces a delayed signal in accordance with the counting characteristics, the clock signal, and the received reset signal. Methods of producing the catalyst and applications thereof are included. More specifically, the invention relates to chaperonin 10 N-terminal variants with enhanced immunomodulatory capacity andor enhanced binding affinity for pathogen-associated molecular patterns andor damage-associated molecular patterns.