The present invention provides compounds having the formula:wherein R1, R2, X1, X2, L1, L2, Y and Z are as defined in classes and subclasses herein, and pharmaceutical compositions thereof, as described generally and in subclasses herein, which compounds are useful as inhibitors of protein kinase, and thus are useful, for example, for the treatment of Aurora mediated diseases. The blocks have formed therein cable channels in a cris-cross manner, diagonally between the corners of each block. They allow source target copy orders to be prepared separately from destination target copy orders. A rib-like convex section 12 is transferred onto the metal plate body 11 by the increased fluid pressure of the hydraulic fluid A and a formed section 22a. A device for recording the compressed data can specify the head of unnecessary compressed information by looking up the specification information, whereby the unnecessary information can be deleted from the recording medium. The emitter includes at least one doped layer of an opposite conductivity type as that of the substrate and the back contact includes at least one doped layer of the same conductivity type as that of the substrate.