The present invention discloses a method of providing anti-oncogenic effects in a subject suffered from colorectal cancer. The repair device includes a top plate with a plurality of top plate screw holes sized and positioned to match the sealing ring screw holes. The dispensing nozzle includes a connecting seal having a series of outwardly directed, flexible fins composed of a first material and an outwardly tapered seal member composed of a second material. In another aspect, a human breast tissue models are disclosed. The storage unit is configured to store the calibration driving program and the coordinate conversion table.