Provided are methods for preventing and treating inflammation and organ injury after ischemiareperfusion, and methods for treating lung injury, comprising administering a milk fat globule epidermal growth factor-factor VIII to a subject. A dropped call is detected between the device and another device as a function of detected signal strength. The toothbrush also includes a dispensing mechanism for manually adjusting a volume of the reservoir and thereby causing dentifrice to dissipate outwardly from the reservoir and head portion as needed.