The present invention relates to chemical compounds having a general formula Iwherein A1-5 and 7-8, D\u2032, L1, L2, R1, R3, R6-8, n and o are defined herein, and synthetic intermediates, which are capable of modulating the activity of Aurora kinase proteins and, thereby, influencing various disease states and conditions related to the activities of Aurora kinases. In many embodiments, for example, devices may be used in minimally invasive techniques for ablating epicardial tissue adjacent one or more pulmonary veins to treat atrial fibrillation. Further, damage by charged particles during a process of doping a high concentration of impurity is also reduced. The optical path converting member includes a lens and an optical path conversion mirror having an entrance surface, an exit surface and a reflection surface, and the lens is provided at least one position selected from the entrance surface, the exit surface, and inside of the optical path conversion mirror. The location data, based on the dead reckoning, can be updated by means of the identifier. The ferrite layer has a composition of 63 to 73% by mass of Fe2O3, 5 to 10% by mass of CuO, 5 to 12% by mass of NiO, and 10 to 23% by mass of ZnO.