The present invention relates to compounds suitable for use in mediating hypoxia inducible factor and for treating erythropoietin-associated conditions by increasing endogenous erythropoietin in vitro and in vivo. The method includes providing a bit stream by the device, where at least one bit in the bit stream represents a feature supported by the device. Further embodiments, forms, objects, features, advantages, aspects, and benefits of the present application shall become apparent from the detailed description and figures included herewith. Related devices are also discussed. The oxidizing agent is believed to be a relatively stable complex of hydrogen peroxide, and has a significant anti-microbial effect on microorganisms, including biofilms, in the water achieved by oxidation of the oxidizing agent with chemical components of the microorganisms. The light-emitting layer is disposed on the first type doping semiconductor layer.