A transmission device for a vehicle component adjuster, such as a seat adjuster, may include a drive screw, a drive member and a load transfer member. A gain control section amplifies, by a predetermined gain, the signal that has been subjected to the frequency conversion to the baseband. The control unit measures a minimum energy value required by the heat generation resistor to discharge liquid. The characteristic mass shift is indicative that the microorganism is growing in the presence of the drug and incorporating the isotopic label into the one or more biomarkers, resulting in change in mass. During operation of the system, software programs are executed and memory transactions are performed. The method includes forming a resist pattern on the substrate; applying an etching chemical fluid to the substrate, wherein the etching chemical fluid includes a diffusion control material; removing the etching chemical fluid; and removing the resist pattern.