The present invention encompasses compounds of general formula wherein R1 to R3 and X are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties. The rotary members are rotated by drive shafts having multiple vein turbine assemblies respectively thereon within the fluid transfer conduit. Each request handler is configured to respond to a client service request of a processing job, and if identified to handle the processing job: to query one or more of the processing regions to identify and assign a particular process handler to service the processing job, and to receive a processing result from the particular process handler. Preferably, the electrode has a circular inner contour so that the gap is annular. Preferably, the hanging, upright tube has an annular lip which can take the form of various flower blossoms in order to replicate the external and internal characteristics of a typical flower.