Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, in a range from 1% to 99% by volume, and an additive in a range from 1% to 99% by volume, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. A request is first received to deploy the distributed application stack including a plurality of software artifacts on the cluster including a plurality of nodes. The method also includes capturing a user’s interaction with a user interface presenting the data set, and storing the interaction in a data store as a refinement action rule.