Automatic pattern matching and shape measurement are enabled by adjusting a brightness level of a microscope image based on information of a local region of the image so that a magnified image of the local region takes on an appropriate brightness and is not affected by brighter peripheral portions of the image, thereby enabling feature extraction of a desired pattern. In one embodiment, a workflow engine operating in the context of a Web browser executes a plurality of executable components comprising a Web mashup. Each fuse box group consists of at least two or more fuse boxes to detect row addresses.