Disclosed is an oil-less toner composition exhibiting good low temperature release and stripping in fixing, enhanced surface gloss of fixed image, andor OHP transparency. A doctor blade device having a seal is also provided. The transfer voltage applying section applies a predetermined transfer voltage, while the recording material passes through the transfer section, so that the transfer current is kept a constant current. Moreover, the present invention provides for methods of treating a variety of pathophysiological cell proliferative diseases. The forming unit, the introducing unit and the dielectric window are arranged in such a way that there longitudinal directions are matched with a width direction of the substrate being conveyed, and orthogonal to the conveying direction. The controller sequentially drives the gate lines to write from the signal lines to the pixel electrodes and, after the write to the pixel electrodes, changes a potential of each of the storage capacitance lines to cause alignment of the liquid crystal layer to make a transition from splay alignment to bend alignment.