A thermally efficient method for the heating a gas permeable wall of a bonded refractory mold wherein the mold wall defines a mold cavity in which molten metal or alloy is cast. By applying such a fluid, the advantages of installing a cable using a liquid flow and using a gas flow may be combined, while the drawbacks respectively associated therewith are obviated. The structure can be revealed with the use of any data set of genetic variants from a particular locus. The second zone effluent is conveyed to a fractionating zone to at least a low boiling fraction and a high boiling fraction, and optionally one or more intermediate fractions. The second chip is electrically connected to the first chip via the chip carrier.