The inventors have found that vitamin K3 and vitamin K5 which may be used in pharmaceuticals and foods or ACNQ, DHNA, or the like which can stimulate the growth of bifidobacteria can inhibit degranulation of basophil-like cells, exhibit a potent degranulation-inhibiting effect, and are useful anti-allergic agents or foods. A target architecture model described in an architecture description language is accessed. The charge plate is produced by providing an electrically non-conductive orifice plate substrate of predetermined thickness, and forming a plurality of charging leads on one of two opposed sides of the orifice plate substrate. The flexure assemblies further provide a counter rotation force to help prevent the beam layer from sticking in an actuated position. These devices apply in particular to laser gyros having monolithic cavities, and in particular to neodymium-doped YAG laser gyros. The pattern may be formed using a poly mold.