A separate nub component between the plate and an intervertebral fusion cage, wherein the nub is attached to the plate. The transceiver includes a digital-to-phase synthesizer having one or more independently variable frequency or phase signal outputs coupled to a transmitter andor to a receiver. The photoelectric conversion element photoelectrically convert incident light into electric charges with an amount corresponding to an amount of the incident light, and accumulates the electric charges. The method generates a second configuration that is based on the first configuration. In addition, antibodies which bind to CCR5, CCR5 variants, and CCR5-binding agents, capable of blocking membrane fusion between HIV and target cells represent potential anti-HIV therapeutics for macrophage-tropic strains of HIV.