A method in a radio network node for handling handover of a user equipment from a first cell to a second cell is provided. More particularly, the invention provides therapeutic compositions that comprise a binding agent that can specifically bind to an epitope that comprises both peptide and carbohydrate on such tumor-associated MUC-1. A first coupling portion is rotatably supported on the axle carrier. In use, actuation of the actuator paddle causes ejection of ink from the nozzle. A decoder is configured to decode the stems according to the set of instructions to create an audio output signal.