There is disclosed a security anchoring device attachable to a sign or the like and anchorable to the ground to prevent or discourage theft and vandalism. The discotic compound has an oriented discotic plane. A toothed housing includes a plurality of ratchet teeth. In particular embodiments, the agents are antibodies or antigen-binding fragments thereof which bind to CD18 or CCR2. 25 dBkm at a wavelength of 1550 nanometers; and a bending loss of not more than 30 dBm when the optical fiber is wound at a diameter of 20 millimeters at a wavelength of 1550 nanometers. The remote user device is authenticated for accessing the postage security account when the data center verifies the remote access message.