The system for selecting a best device for rendering a color document involves first determining the types of color data included in the color document to be printed. Stripped fibers are positioned such that they protrude with respect to an end face of a V-groove substrate provided with V-grooves, and the peripheral adhesive is formed flush with the end face of the V-groove substrate without protruding. A portion of the heat exchange plate, or a second heat exchange plate, includes transfer lines for syrup and for carbonated water. A change in the N-dimensional signal vector over time is then determined and compared to a predetermined threshold to establish whether local activation has occurred on the channel of interest. In particular, the opiate alkaloids produced by the process of the invention are typically intermediate compounds that may be utilized to produce a variety of biologically active alkaloids including buprenorphine and diprenorphine.