The present invention is a MTP plate that has a first embodiment with a profile having bilateral mirror symmetry of the about a transverse plane with an angle of about 5\xb0 for dorsiflexion and an angle of about 10\xb0 for valgus. The first receiver element has lower power consumption than the second receiver element does when energised. The optical-communication receive part receives an external light signal by using an image reading part. The microchip includes an air introduction path formed of a groove provided on an outer surface of the microchip and coupled to the reagent retaining portion for introducing air into the reagent retaining portion, and a sealing portion provided so as to be detachable from the microchip for sealing the air introduction path. First information associated with a first access and second information associated with the second access to the location is determined. The invention also provides methods of using the novel class of acidic amino aciddicarboxylic acid derivatives of the general formula ZOC\u2014m\u2014COOH, wherein: m=2, 3 or 4; Z is OH or NH2; one R in the compound is from the group consisting of SO3H, OSO3H, CH2\u2014SO3H, CH2\u2014OSO3H, and NHSO3H, and the remaining Rs are H or NH2, for inhibition of osteoclastogenesis.