The apparatus includes a friction stir welding tool, a local clamping means, and an interface that joins the tool and the local clamping means. The first step is a step of calculating a consumption current amount of a layout target circuit based on circuit information. The VOR system also includes an information exchange having a producer database configured to store a producer profile having current location and status of the producer. These genetically modified animals can be used to predict the side effects of drugs such as SGRF antagonists. Also, the CS measurements may be high-pass filtered to attenuate background light variation.