A software application development system and method of developing and running software is disclosed that allows multiple developers to access, develop and run a common software application simultaneously; even while others are running and using the same software application. The two staple legs enter the tissue until the tissue applies a compressive force to a compression device disposed at least partly between the two staple legs. Such polymers can also be readily and economically transformed into particles vectorizing active principles according to the grafting rate of the hydrophobic groups, said particles being able to form stable aqueous colloidal suspensions. The second flip-flop has a data input terminal responsive to an output of the first flip-flop, and a clock terminal responsive to the inverse of the feedback clock. As the substrate assembly moves relative to the polishing pad, regions of the front face are separated from the abrasive particles in the polishing pad by a lubricant-additive in the lubricating planarizing solution. The adjusting device includes a drive shaft, a drive unit, a driven unit, and an adjusting unit.