A method for high spatial resolution examination of a sample, the sample to be examined including a substance that can be repeatedly converted from a first state into a second state, the first and the second states differing from one another in at least one optical property. The needle has a locking device which can be used with or without a syringe. The gripping device spreads shock and concussive forces evenly through the device, distributing pressure over the entire surface of the hoof. Being pressed downwards, the electrically conductive slice of the chip module presses the elastic arm, and the elastic arm bends toward the second sidewall and deforms, so that the chip module moves toward the second sidewall. In the most preferred embodiment, a coaxial cryocable 10 has a center conductor 11 surrounded by a dielectric 12 surrounded by an outer conductor 13 which has a thickness between about 6 and 20 microns.