Substantially pure human cyclin-dependent kinase-like proteins PITALRE and PISSLRE and isolated protein complexes that comprise PITALRE or PISSLRE are disclosed. The system and method includes three frameworks: a Design Time Framework, an Object-Service Framework, and a Run Time Framework. Then, resist having a cutout pattern is formed. The actuator is operated from a location remote from the control module and the contacts operate independently from the circuit breaker. According to one embodiment, values in a first proof corresponding to a first statement are precomputed, a request for a second proof is received from a challenger, and the first and second proofs are completed. The multiple processors each run an Open Communication system that controls how data is transferred between processors based on data content as opposed to the links that connect the processors together.