Methods of treating a high salinity liquid, such as seawater, containing boron are provided, including adjusting the pH of the liquid to about 8 to about 9. More particularly, integrated processes of the invention comprise separations by means of one or more devices using polymeric membranes coupled with recovery of purified products by means of fractional crystallization andor selective sorption. A number of bits that differ between the respective numerical values of each pair of rows of the routing network indicates a number of row traversals necessary to traverse from a first row of the pair to a second row of the pair.