An HVAC assembly including an HVAC case disposed in a passenger compartment of a vehicle for delivering air at a passenger side foot well includes a duct coupled to an opening on the HVAC case. Methods and compounds useful in treating other disorders such as amyotrophic lateral sclerosis, Huntington’s disease, Parkinson’s disease, and pervasive developmental disorders such as autism are also disclosed. The mapped integrated-service data model is merged with the tenant-customized data model to obtain the tenant service context for the tenant.