The present invention provides novel pyrazoles that are useful as cannabinoid receptor antagonists and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, hepatic disorders, andor cardiometabolic disorders. The method for treating a medium by saturating it with useful substances emitted by plants involves supplying a gaseous medium to a chamber containing vegetative or cut plants and passing the gaseous medium saturated with plant excreta through the medium undergoing treatment. As another method, wheels are provided for the plate member on which is mounted the control box. Each media service provides its own file transport parameters defining procedures for obtaining media assets therefrom and writing media assets thereto; the transport service determines particular protocols for each transport operation based on the information provided by the sender and recipient media services. The external toothing is divided into a plurality of tooth segments which, as viewed in the longitudinal extent, alternately extend from the base body in opposite directions. The x-ray detector includes a split scan line that activates the pixels and a data line that conducts charge indicative of the x-rays.