The invention involves identification of a mechanism of \u03b2-amyloid peptide cytotoxicity, which enables treatment of conditions caused by \u03b2-amyloid peptide aggregates by administration of compounds which antagonize the mechanism of cytotoxicity. Then, update information is either received from the provider or is generated. As an example, only the even word lines are programmed with the odd WLs left unprogrammed. The opening portion is provided in a central part of the flat plate portion. Also provided are sandwich wall panels and double wall panels employing the load transfer device and methods for manufacturing sandwich wall panels and double wall panels employing the disclosed load transfer device.