The present invention provides a technique to efficiently rearrange data in actual regions. In addition, the invention refers to the use of dextran sulfate, or a pharmaceutically acceptable derivate thereof, for manufacturing of a medicament for treatment of morphological disruption of cell transplants and graft-rejection of cell transplants caused by IBMIR. Based on one or a combination of explicit, implicit and transactional input from the patient and in consideration of the IMD data underlying therewith, the patient is guided to consult with the most pertinent database. A second front surface metal layer which forms a front surface electrode is formed on the first front surface metal layer.