An adjustable tibial trial insert includes an upper plate having an upper articular surface and a lower plate. The end devices are each associated with at least one of a space, a system, or a subsystem for at least a portion of a building or a campus. The first wall is co-planar with first edges of the side walls. The agent assessed may include a hazardous agent, a chemical agent, a biological agent, a microorganism, a bacterium, a protozoan, a virus, and combinations thereof. Also disclosed are methods of treating a bacterial disease in a mammal by administering such pharmaceutical compositions. The design is usable without modification for a variety of craft.