Heterogeneous compound databases can be searched for compounds which are likely to have the same biological activity as a known molecule. In the process for producing acrylic acid from glycerin, a molar ratio of oxygen to glycerin in a raw material gas is set to be not lower than 0. A digital to analog converter is used to convert the uncompressed digital data into another analog signal. In response to this comparison yielding a matched player-profile data set, the method includes activating one or more personalized attributes at the gaming terminal associated with the matched player-profile data set. A Fourier transform algorithm is applied to the surface gradients to reconstruct a surface that corresponds to the optical tissues of the eye. It is then possible to provide semiconductor devices and a manufacturing method thereof which enhance the reliability and productivity of the semiconductor devices by probing a large number of integrated circuits or a large size integrated circuit in the same time.