A novel class of compounds of the general formula, their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments are described. Some embodiments of the invention provide an AF system that includes one or more interferometers for measuring a distance to a wafer surface or a reticle surface. The electron beam is reciprocally oscillated in a circumferential direction X approximately orthogonal to a radial direction Y of the disk and deflected in the radial direction Y, thereby filling in the element shape. A sample potentially containing the target antigen is introduced into the capillary tube. The high resolution signals can be concurrently displayed as one or more image areas on a display device in any contemplated size, number and arrangement. A shock balance controller may also include a structure configured to support the shock balance controller, the structure having a chamber, a port, and a housing assembly, and a bladder coupled to the structure using the housing assembly, the bladder and housing assembly being configured to transfer energy between the bladder and the chamber.