A geolocation method is applied for accurate targeting of a target using an airborne beacon as a pseudo star generated by a high altitude vehicle, and using optical sensors by a low altitude vehicle for imaging the beacon and target for generating accurate relative GPS positioning of the target for improved the geolocation of the target preferably for precise delivery of a payload to the target. Such transgenic animals provide a useful animal model system for human B cell chronic lymphocytic leukemia. The temperature-equalizing member moves from a separate position to a first pressure-contacting position at which the temperature-equalizing member pressure-contacts the fixing belt, and further moves to a second pressure-contacting position while maintaining a pressure-contacting state with the fixing belt.