The present invention relates to small molecule antagonists of Bcl-2 family proteins such as Bcl-2 andor Bcl-XL. Coupling magnet forms a magnetic coupling with drive magnet. The printing apparatus stores the result of detecting the edge of another medium to be printed, and, when printing on the medium to be printed, it reads out the stored detection result and determines the print start position based on that detection result. In response to a clamp pulse the clamp arrangement couples said clamp voltage to said color difference signal. The output beam is thus shaped to define at least two beams comprising at least the first portion and a remainder of the output beam which is propagated along the Z axis without deflection by any reflective member, with the first portion of the output beam being oriented approximately parallel to the un-deflected remainder.