There is disclosed a process for transporting fracture fluid additives underground to oil and gas wells by attaching a fracture fluid additive to an ion exchange resin and flowing the ion exchange resin underground and thereafter releasing the frac fluid additives from the ion exchange resins and also there is provided the use of an ion exchange resin as a proppant and a frac fluid lubricant. Specifically useful are VEGFR modulating agents capable of promoting liver growth. The slot structure identifies at least a first location of a reference signal within a slot. Ambient cooling air may flow in series through the upper charge air cooler portion and the upper radiator portion, and also through the lower charge air cooler portion and the lower radiator portion.