This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases. A polysilicon layer is formed over a substrate and a metal layer is formed on the polysilicon layer. An electric nerve stimulation technique, such as vagus nerve stimulation, is administered to the patient in conjunction with a magnetic nerve stimulation technique. Also claimed are a medication chamber for use in medicating an airstream and a method of medicating an airstream. A virtual world providing subsystem, coupled to the server subsystem, provides the virtual world data, which produces data that presents the virtual world.