The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K. The rechargeable implantable medical device can be a wide variety of medical devices such as neuro stimulators, drug delivery pumps, pacemakers, defibrillators, diagnostic recorders, and cochlear implants. The method comprises accelerating the main actuator during coarse positioning of the transducing head and applying control pulses to the microactuator during coarse positioning by the main actuator to eliminate oscillation of the microactuator during and after coarse positioning. An LDD region is formed on the semiconductor substrate. The detection that users are having difficulty with the application and proactive intervention when such difficulties are detected may help to prevent the users from abandoning the application.