The invention relates to the identification and selection of novel biomarkers and the identification and selection of novel biomarker combinations which are differentially expressed in individuals with mild osteoarthritis as compared with individuals without osteoarthritis. Preferably, the game is a step-by-step strategic or random game, whereby a player andor participant user starts at an opening \u201cstarting point\u201d and proceeds from one interval location to another. That is, in order to form an image by print scans of the printhead on a single print area on a print medium, image data are acquired in correspondence with the respective scans. A device snapshot storage in the customer IHS stores the device snapshot of the customer IHS. The multiplication and logical shift operations are performed on each of the sub-quotients according to a procedure derived from long-division techniques. In particular, the invention relates to methods of isolating mesenchymal stem cells from bone marrow, for repairing or inducing formation of bone, without prior culture expansion of the mesenchymal stem cells.