An exemplary embodiment includes acquiring an electroneurogram of the right carotid sinus nerve or the left carotid sinus nerve, analyzing the electroneurogram for at least one of chemosensory information and barosensory information and calling for one or more therapeutic actions based at least in part on the analyzing. Initiation of the via-hole and fabrication of the calibrated pattern from one surface, such as the front side, of the integrated circuit wafer and completion of the via-hole from the opposite surface of the wafer are contemplated. and a crystallinity of at least 20%.