A modulation device and method, and a demodulation device and method are provided. Individual interchangeable modules connected through the wiring harness establish finite and discrete electronic relationships through the guitar’s existing electric components to produce a plurality of selectable desired tonality sounds from a single guitar. A circumferential shape of the element forming region has a first side extending along the first direction. In addition, the semiconductor device includes a recess extending from a top surface of the isolation structure. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The present application provides for an emulsifiable concentrate excellent in emulsion stability which comprises pyriproxyfen, alkylarylsulfonic acid salt, polyoxyethylene styrylphenyl ether, polyoxyethylene castor oil, fatty acid C1-C6 alkyl ester, and aromatic hydrocarbon in specified amounts.