The present invention relates to benzimidazole carboxamides of formula I, the use of the compounds of formula I of as inhibitors of one or more kinases, the use of the compounds of formula I for the manufacture of pharmaceutical compositions and methods of treatment, comprising administering said pharmaceutical compositions to a patients. The methods generally comprise applying acid to a portion of the substrate; coating the substrate with a coating comprising a component that reacts with the acid; and removing the coating from the portion of the substrate to which the acid has been applied. The data related to the picture size indicates a size of the picture corresponding to the picture signal or an output area, which is a pixel area to be outputted in decoding in a whole pixel area coded in the picture signal coding. In an alternative embodiment the guide has two independent and non-intersecting bores which allow the simultaneous placement into the tibial tunnel of two separate guide pins to guide the formation of two tibial tunnels on the tibial plateau. When the ultrasonic acoustical wave generator is excited, it applies ultrasonic energy to the pressurized liquid contained within the chamber as the liquid passes through the housing without mechanically vibrating the exit orifice.