The present invention is directed to novel culture methods and devices in which living cells or subcellular biocatalysts are immobilized in an open chamber defined by two rotating disks. WIPS represents the web page by its layout and logic structures. Each new roll of tagslabels starts interrogation with the first of the settings. The invention also provides a system for producing the mutant pyrogenic toxins and methods of use for the mutants. The reception processing units, when the wideband reception signal is input, apply reception processing to divided signals obtained by extracting a part of bands of input signals on the basis of the local signals.