This invention relates to compounds of Formula as Pi3k inhibitors for treating autoimmune diseases, inflammatory disorders, multiple sclerosis and other deseases like cancers. The seperating layer or the protective substrate having a guide groove spirally or concentrically formed on the surface, and the respective inclined planes on the inner perimeter side and the outer perimeter side of the guide groove having inclined angles \u03b1 and \u03b2 with respect to the bottom face of the guide groove. The device may be further operable to limit or prevent restraint anchor displacement and the distortion of said deformable member under quasi-static load conditions in order to meet motor vehicle static loaddisplacement anchorage performance requirements applicable to certain anchors. The comparator may include a preamplifier, a latching circuit, a level shifter, and a flip-flop coupled in series. The CIRs are compared to operator defined thresholds. In specific embodiments, the mobile device is equipped with short range communication mechanisms or some other form of wireless communication that allows for the mobile device to communicate customer program verification data, offer data andor necessary payment data to a properly configured Point-Of-Sale device, such as a cash register, card reader device or the like.