An integrated circuit chip, useful as an electronic thermostat, comprises a temperature sensor for providing a signal corresponding to ambient temperature. The indole derivatives according to the present invention are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions. In one embodiment, components of an interactive video system can operate to adaptively manage and control video payload parameters to adapt to various communication conditions associated with a real-time or near-real time interactive video environment. An HTTP request is made to the interface or online application based on the HTTP request and the user test application processes an HTTP response from the interface or online application and transmits the HTTP response to the participant as if the participant made the request directly from the remote interface or online application.