The current invention provides compounds having a structure according to Formulae 1, 2, 3, and 4:wherein the A-ring, B-ring, C-ring, m, n, R25, R50, and R51 are as described in the specification. The transfer table includes a top surface and a bottom surface, a first current input portion at the bottom surface, a first power connector embedded at the top surface, and electrically connecting to the first current input portion, and a first signal cable connector arranged on the top surface. Viewpoints of the two or more viewers are determined based, at least in part, on the head positions. The difference h in depth of the recessed or projecting portion is set to. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes. Exemplary changes include a change in a physical dimension or stiffness of the template molecule, a change in electrical conductivity of the template molecule and a change in the energy required to dissociate the target molecule and the template molecule.