The present invention is based on the identification of synaptic vessel glycoprotein SV2 as the BoNTA receptor and the further identification of various BoNTA-binding fragments of SV2. One embodiment of the present invention relates to a method for processing information, comprising determining if a first identifier associated with the information is acceptable and assigning a second identifier to the information. Hollow stabilizing component provides for a first additional guide and support for a catheter sheath from the distal end of the needle.