Based on a free-form narration of a patient encounter provided by a clinician, it may be determined that one or more clinical facts could possibly be ascertained from the patient encounter. A conifer seedling is inoculated with an isolated endophyte when the conifer seedling is susceptible to colonization by the endophyte. Also described is a chromatography scheme and method for purifying monoclonal antibodies, wherein the anion exchange sorber is placed downstream of an affinity column and optionally one or more polishing devices such as cationic exchange columns.