In response to a master receiving a memory access request indicating a target address, the master accesses a first cache directory of an upper level cache of a cache hierarchy. A synthetic wood 1A includes a body 2 defining a core thereof and formed of a polystyrene or polypropylene foam and an outer layer 3 covering the body and formed of a weather-resistant synthetic resin that is unfoamed or foamed at a low expansion rate. The simulation player software product enables an end user to run the simulation model based upon the information in the simulation content file, but does not allow the end user to add or remove component models, subsystem models or interconnections of the simulation model. Pulse width modulation of the electronic driver 314 in conjunction with selective actuation of either low side driver 316, 330 results in rapid response to system control algorithms whereby each actuator L1 or L2 may be de-activated in a relatively quick manner thereby improving vehicular control. In particular the invention concerns blackberry leaf extracts and preparations and medicaments containing them, as well as their use to inhibit irritating and inflammatory skin conditions.