Cosmeticdermatological compositions for topical application and useful for the treatment, e. Pixel signal which have undergone the noise reduction processing and stored in advance in a memory are read so that colors of corresponding pixel signals do not shift. The medium is then supplied in excess with all substrates required for production of the fermentation product and in growth limiting amounts with a substrate complementing the auxotrophy. In a second preferred embodiment, an out-of-order dispatch unit is used such that not only are primitives executed concurrently; but, the primitives may be executed in any order when dependencies are detected.