One embodiment of the present invention provides a system for communicating and performing synchronization operations between a main thread and a helper-thread. According to an embodiment of a method, a node of a replicated storage network is assigned to be an owner of a data block to issue write memory block commands. The hub has axle roller bearings. Therefore, the disclosed in-system memory testing method complements other test techniques like BISTPOST that are conventionally used only at the time of system boot up. The infrastructure includes an integrated suite of tools including a methodology development tool, multiple user interfaces including a methodology finder and a methodology browser, and an estimating tool that integrates the methodology content into the project planning process. The method can be used before and after treatment of liver fibrosis.